http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019089858-A2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e974c8a148aa6bf505c7e049484889e |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-70514 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-70517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5091 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5017 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56972 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57426 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57492 |
filingDate | 2018-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c14b6cfefc2a25c7ffbcdcbefcd468e1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d449659237e59bd7c7f87f3bbe6fcaf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_429624b7b6f219b05580400633344b66 |
publicationDate | 2019-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2019089858-A2 |
titleOfInvention | Methods of assessing or monitoring a response to a cell therapy |
abstract | Provided are methods and articles of manufacture for use with cell therapy for the treatment of diseases or conditions, e.g., cancer, including for predicting likelihood of the subject responding to a therapy, such as a cell therapy, e.g., a chimeric antigen receptor (CAR) T cell therapy. In some aspects, the predicting is based on detecting certain biomarkers of immune cells associated with and/or that correlate with response following administration of the therapy. The methods generally involve detecting a marker by assaying a biological sample from a subject that is a candidate for treatment, optionally with a cell therapy, to determine if the subject is likely to respond to the therapy. The present disclosure also provides methods for treating a subject having a disease or condition, in some cases involving administration of the cell therapy, based on assessment the biomarker. Also provided herein are reagents and kits for performing the methods. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019200325-A1 |
priorityDate | 2017-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 3248.