| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8073450a491d200d05b09b9beb6f0ec6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4319fe3d827bd24add491d4ed90e7692 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-20 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6837
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-22 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
| filingDate |
2018-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e064a00cc37be1c798f6b41b8ae5826e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59d10be387e3a749ccf54f0d45295efc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3e21e43cf4f4ec733b5bb9b73fec863
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d90dcbedfc5dbb1ffcf005b29d15ad87 |
| publicationDate |
2019-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2019089761-A1 |
| titleOfInvention |
Crispr protein inhibitors |
| abstract |
The embodiments disclosed herein utilize fluorescence polarization based preliminary screen to identify a putative set of Cas inhibitors from an initial set of candidate inhibitors. The primary screening assay is followed by secondary screening assay to validate the putative set of inhibitors selected by the preliminary screen. In some embodiments, the present disclosure includes compositions and methods are provided for the inhibition of the function of RNA guided endonucleases, including the identification and use of such inhibitors. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021198275-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3889255-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114088783-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11021719-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3831940-A1 |
| priorityDate |
2017-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |