| abstract |
The present invention provides, in one aspect, compounds for regulating, limiting, or inhibiting the expression of AVIL (advilin), as well as methods for their manufacture, pharmaceutical compositions comprising them, and methods of treating disorders associated with dysregulation of AVIL using them. In some aspects, the compounds, compositions and methods of the invention may be used to treat disorders or diseases in which regulation, limitation, or inhibition of AVIL expression may be clinically useful, such as, for example, cancer treatment. This abstract is intended to serve as a search tool for research purposes in the state of the art concerned and is not intended to limit the scope of the present invention. |