| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8528ff66470c896b6da8ed059464e31f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_43e0b7356fbc54935a76c8061c75b154 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-31 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57492
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-3092
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5011
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5055 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| filingDate |
2018-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b428488ef22adbf64a295a97e2593dda
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_232aa9005c2333135e5ab32868a71da8 |
| publicationDate |
2019-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2019081714-A1 |
| titleOfInvention |
POSITIVE MACROPHAGES TO PODOPLANIN |
| abstract |
The invention relates to the technical field of tumor metastasis and peritumoral lymphangiogenesis. Specifically, podoplanin on a subset of tumor-associated macrophages has been identified as a target for the treatment or inhibition of tumor metastasis and peritumoral lymphangiogenesis, and podoplanin positive macrophages have been identified as biomarkers for lymphatic metastasis. The invention further provides assay methods for identifying compounds capable of neutralizing podoplanin positive macrophages, and methods and kits for tumor analysis or lymphatic vessel analysis. |
| priorityDate |
2017-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |