| abstract |
The present invention relates to the novel oral dosage form for the sustained release of crocin-1, an active constituent of the extract or fraction of Crocus sativus and its method of preparation, the extract being wet granulated using excipients, biodegradable polymers and / or non-biodegradable polymers alone or in combination. The formulations are useful for the treatment of chronic inflammatory diseases in which NLRP3 inflammation is implicated. |