| abstract |
The present invention relates to a dihydropyrimidine compound and use as a medicament, in particular as a medicament for the treatment and prevention of hepatitis B. More particularly, the invention relates to a compound of formula (I) or (Ia ), or a stereoisomer, a tautomer, an N-oxide, a solvate, a metabolite, a pharmaceutically acceptable salt or a corresponding prodrug, the variables in the formulas being as defined in the description. The invention also relates to the use of the compound of formula (I) or (Ia), or an enantiomer, diastereoisomer, tautomer, hydrate, solvate or a pharmaceutically acceptable salt thereof, as a medicament, in particular as a drug for the treatment and prevention of hepatitis B. |