| abstract |
The present invention provides novel compounds, reagents, systems and methods for detecting an NRTI-associated metabolite in a biological sample, and their use for monitoring adherence to prophylactic pre-exposure therapy or anti-retroviral therapy. These reagents include NRTI derivatives, analogs, conjugates of NRTI derivatives, as well as antibodies directed against them, which are useful for antibody-based methods, such as a lateral flow immunoassay. , and for other devices on a place of care. |