| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_47f079fed01315e7f0429c70e359a9b7 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5169
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5123
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7048
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1075
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-19 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-107
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7048 |
| filingDate |
2018-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bfe102d6344c40a17d0238180f89c54c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ed436619d0a77aa7f69efb64f4ac2fe |
| publicationDate |
2019-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2019073371-A1 |
| titleOfInvention |
PHARMACEUTICAL COMPOSITION COMPRISING ALBUMIN-LIPID HYBRID NANOPARTICLES |
| abstract |
The invention relates to pharmaceutical compositions comprising albumin-lipid hybrid nanoparticles having an average particle size of less than about 500 nm and a polydispersity index of less than about 0.6, wherein the nanoparticles contain (i) a therapeutically effective amount of anticancer agent, (ii) human serum albumin, (iii) a lipid component comprising cholesterol and lecithin, and optionally, (iv) a targeting ligand; the molar ratio of human serum albumin to the lipid component being from about 1/1 to about 1/20. The invention further provides methods of treating cancer using these compositions. |
| priorityDate |
2017-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |