http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019071023-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_68c213ba9952360f439567152e047b18 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y209-01001 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-11 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 |
| filingDate | 2018-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d52d413e342b081c0c8f33e5b0302c93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fffa2c5b14655c4d955cd6a0f4dee7bc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f5786d6b388b9048f9163f9fbaf415c |
| publicationDate | 2019-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2019071023-A1 |
| titleOfInvention | COMPOSITIONS AND METHODS FOR MAKING POLYPEPTIDES CONTAINING SELENOCYSTEINE |
| abstract | The invention relates to non-naturally occurring tRNAsec and methods of use thereof for the recombinant expression of genetically engineered proteins to include one or more selenocysteine residues. The non-naturally occurring tcRNAs can be used for the recombinant manufacture of selenocysteine-containing polypeptides encoded by mRNA without the need for a SECIS element. In some embodiments, the selenocysteine-containing polypeptides are made by co-expressing non-naturally occurring tcRNAs in a recombinant expression system, such as E. coli, with SerRS, EF-Tu, SelA or PSTK and SepSecS, and an mRNA having at least one codon that recognizes the tRNAs anticodon of unnatural origin. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020232312-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020232314-A1 |
| priorityDate | 2017-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 195.