abstract |
The present invention provides a unified cell differentiation protocol for obtaining photoreceptor cells, retinal pigment epithelium, and retinal 3D organoid from pluripotent stem cells. The present invention also relates to photoreceptor cells, a retinal pigment epithelium and a 3D retinal organoid obtained from pluripotent stem cells. The invention also relates to a pharmaceutical composition and a drug comprising photoreceptor cells, retinal pigment epithelium and retinal organoid 3D as described in the present invention. |