| abstract |
The present invention provides, inter alia, compositions and methods for treating cancer. The compositions according to the invention comprise, for example, a chimeric antigen receptor or a bispecific antibody comprising a free immunoglobulin light chain VL, inter alia, useful for targeting and eliminating human mantle cell lymphoma cells ( MCL). The compositions according to the invention can be used, for example, for therapeutic and diagnostic purposes, because of their ability to bind differentially to MCL versus non-cancer cells. |