| abstract |
The invention relates to an amorphous folate salt. The salt consists of an anion of folate and an organic cation. The folate anion is selected from the group consisting of 5-formyl- (6S) -tetrahydrofolic acid, 10-formyl- (6R) -tetrahydrofolic acid, 5-methyl- (6S) -tetrahydrofolic acid, and , (6S) -tetrahydrofolic acid, 5,10-methylene- (6R) -tetrahydrofolic acid, and its oxidized derivatives JK12A and Mefox, and the cation is an organic compound selected from the group consisting of arginine, choline, acetylcholine, 1,1-dimethyl biguanidin phenylethylbiguanidine, betaine methyl ester and dimethylanninoethanol. The cation is an organic compound having complementary pharmacological activity. |