abstract |
The present invention relates to nucleic acids, expression vectors, host cells for producing RNA-dependent RNA polymerase (RdRp) polypeptides of viruses such as Ebola virus. The present invention also provides methods and substrates for analyzing the activity of a RdRp polypeptide or RdRp complex. The invention also relates to inhibitors of RdRp polypeptides of viruses such as Ebola virus for use in the treatment or prevention of a viral infection. |