abstract |
The present invention relates to compounds of formula (I), wherein R1 to R3 are as defined in the claims, or pharmaceutically acceptable esters, salts, hydrates or solvates thereof, which are useful as DAAO inhibitors, as well as pharmaceutical compositions containing them and their use as modulators of DAAO activity, D-serine levels, D-serine oxidation products and NMDA receptor activity in the nervous system of a mammalian subject. |