| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ca82d85ba526a9d85bc53f9c7a5be440 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y305-04005 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-79
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y305-04005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-78
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-102 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-79 |
| filingDate |
2017-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0fb5b407ad4b64f12304776eec5f6807
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df68f90cd2fc68d7650ddc831600a844
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_201bb78e16c5db3d317db65488d344dc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4fb3521388df3b2777f39f9949376a93
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd5df32d8a561959bac7cdfc18de7b15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_089847b8424e9781c2f87078426eb43e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d858ec28da4a57d8a84f9610ca586e09 |
| publicationDate |
2019-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2019041296-A1 |
| titleOfInvention |
SYSTEM AND METHOD FOR EDITING BASES |
| abstract |
The invention relates to a system and a method for editing databases based on a CRISPR / Cpf1 system. The base editing system uses Cpf1 to recognize features of a 5'-TTTN-3 '(PAM) sequence, and performs base editing in adenine and thymine-rich regions in genomic DNA. The base editing system comprises a Cpf1-BE0 expression vector and / or a Cpf1-BE expression vector and / or a Cpf1-BE-YE expression vector and / or a Cpf1-expression vector. BE-UGI and / or an RNA product expressed by the Cpf1-BEO expression vector and / or an RNA product expressed by the Cpf1-BE expression vector and / or an RNA product expressed by the Cpf1-BE-YE expression vector and / or an RNA product expressed by the Cpf1-BE-UGI expression vector and / or a protein product expressed by the Cpf1-BEO expression vector and / or a product protein expressed by the expression vector Cpf1-BE and / or a protein product expressed by the Cpf1-BE-YE expression vector and / or a protein product expressed by the Cpf1-BE-UGI expression vector. The invention also relates to a method of editing bases in the genome of a eukaryote. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021072250-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110117621-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110117621-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2605514-A |
| priorityDate |
2017-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |