| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bc2b03342511abc88f60c63f2acd96d0 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-71
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N2005-1094 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-015
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-045
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0662
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0633 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-752
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0797 |
| filingDate |
2018-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7df5533b087fe5d0ba498d8a5cba8cf6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e68aff79c5cd46607d34a18eacdbabde
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b6853912e4e5da4b23bbe3c00001079
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b30396c8710e6d58fd696eedbe30b85a |
| publicationDate |
2019-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2019040772-A1 |
| titleOfInvention |
MONOTERPENE ACTIVATORS OF ALDEHYDE DEHYDROGENASE 3A1 AND METHODS OF USE |
| abstract |
The present invention provides methods of increasing the proliferation of adult salivary stem cells, and methods of protecting adult salivary stem cells and improving salivary gland function. These methods include contacting adult salivary stem cells in vivo , in vitro or ex vivo with a therapeutically effective amount of at least one isolated monoterpene and subjecting adult salivary stem cells to radiation treatment. Increased proliferation of adult salivary stem cells can be implemented to increase the number of adult salivary stem cells and improve salivary gland function in an individual undergoing radiotherapy for head and neck cancer . The methods also include treating an individual with dry eye syndrome with a therapeutically effective amount of at least one isolated monoterpene. |
| priorityDate |
2017-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |