| abstract |
The present invention relates to a novel tryptophan hydroxylase inhibitor and a pharmaceutical composition comprising it, the novel tryptophan hydroxylase inhibitor having an excellent inhibitory effect on TPH1, and can thus be used in a useful manner for the prevention or treatment of disorders, such as metabolic disorders, cancer, disorders of the digestive or cardiovascular system, related to the activity of TPH1. In particular, the novel tryptophan hydroxylase inhibitor has an excellent treatment effect on inflammatory bowel disorders, and can therefore be usefully useful for the treatment of inflammatory bowel disorder. |