| abstract |
The present invention provides libraries containing polynucleotides, wherein one of the polynucleotides encodes an antibody light chain having specific hypervariable regions HVR-L1, HVR-L2, and HVR-L3. The present invention further relates to libraries containing polynucleotides encoding a plurality of single antibodies, wherein each antibody comprises a heavy chain variable region and a light chain variable region. The present invention also relates to antibodies, polypeptide libraries, vector libraries, cells, non-human animals, antibody light chains, methods of making an antibody library, kits, and processes for producing a bispecific antibody associated therewith. |