| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42e94091a4fc81b8d0237117707cc7ee |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-056
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4402
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4406
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4409
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-427
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4184
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D235-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D235-18 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4184
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-18 |
| filingDate |
2018-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd3a35652e9acc84022dbf5feff79401
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d811c4076340b676ca2cf141eab53301
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_300953eeb9d44831eb04ba92fe4950ce
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b69c3e14cf1ef527282c650ea8f74f8c |
| publicationDate |
2019-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2019036024-A1 |
| titleOfInvention |
2- (1,1'-BIPHENYL) -1H-BENZO [D] IMIDAZOLE DERIVATIVES AND RELATED COMPOUNDS AS AGONISTS OF APELIN AND APJ FOR THE TREATMENT OF CARDIOVASCULAR DISEASES |
| abstract |
The invention relates to compounds of formula (I): wherein all variables are as defined in the specification. The compounds according to the invention are agonists of apelin and APJ for use in the treatment of cardiovascular diseases. The preferred compounds according to the invention are 2- (1,1'-biphe-1H-benzo [d] imidazole derivatives.) The invention further relates to compositions comprising the compounds, and compounds for use in methods of medical treatment. |
| priorityDate |
2017-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |