| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_60e66be87630d7cef0ce770e1d898eec |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-315
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3231 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-115
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-99 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-16 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-99
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-115
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
| filingDate |
2018-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_540850b09bb95d281647559ec82252bf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_205abac3bf0bb6faae5951e341d2fa0b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b3e1791932bff115a9d3683d52d670d |
| publicationDate |
2019-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2019035485-A1 |
| titleOfInvention |
NUCLEIC ACID APTAMER FOR INHIBITING GENOME EDITION ENZYME ACTIVITY |
| abstract |
A nucleic acid aptamer that inhibits the binding activity or enzymatic activity of a complex comprising a guide RNA and a nuclease to a target nucleic acid, and the region (1) to (3): (1) from a sequence that recognizes the guide RNA A single-stranded guide RNA recognition region comprising a guide RNA recognition oligonucleotide, (2) a first neck oligonucleotide consisting of said PAM sequence, and a second one consisting of a sequence having complementarity to said PAM sequence A neck region comprising a neck oligonucleotide, and (3) a double stranded structural stabilization region comprising a first structural stabilizing oligonucleotide and a second structural stabilizing oligonucleotide, Wherein said region (1) is linked to said second neck oligonucleotide to form a loop structure or a flap structure, and said regions (2) and (3) There forms a stem structure together are connected, nucleic acid aptamers. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111424034-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111424034-A |
| priorityDate |
2017-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |