abstract |
The present invention relates to antibody sequences discovered in antibodies that bind to human CD38 protein. In particular, the present invention relates to human anti-CD38 antibody sequences. Antibodies and antigen-binding portions thereof comprising such sequences have characteristics compatible with pharmaceutical manufacture and development and can be produced as fully human antibodies (e.g., fully monoclonal antibodies). or antigen-binding fragments) which may be useful for medical methods and compositions, particularly for the treatment of cancer. |