abstract |
The invention relates to tetramaleimide linkers and the use thereof, more particularly the invention relates to compounds of formula I and their use in the preparation of antibody-drug conjugates (CAM). The CAMs obtained from said tetramaleimide linkers exhibit high homogeneity and stability, and could be used effectively for the treatment of various diseases including tumors. The definition of groups in formula I is identical to that given in the description. |