| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3f765b82ed849c5975338f3085e91df2 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5011
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5017
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-44 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
2018-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b017fec9cda9e49a6bd1208a98bfe96
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_174b2b0e30c275e64ca0f5eb42eae9c9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9aee182e920a066ccca77a0828871054 |
| publicationDate |
2019-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2019033123-A1 |
| titleOfInvention |
DRUG ASSOCIATIONS FOR TARGETING MULTIPLE MUTATIONS IN CANCER |
| abstract |
The present invention provides methods of treating cancer in a patient. The method comprises: (a) defining a set of substances targeting pathogenic genes identified by screening in a sample of cancer cells from a patient by NGS or other technique, (b) identifying at least two target genes in cancer cells, each containing an operable mutation, (c) testing, by in vitro cell culture experimentation, the efficacy of one or more of the substances (sequentially or concurrently administered) targeting the mutation operable for each of the two or more target genes that have been identified and (d) the designation of potential effective therapeutic options that will be used to treat the patient's cancer. |
| priorityDate |
2017-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |