| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f2d3599fb8f8f479dba95ca9bb504884
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7fd0d13a41c5b0a065e506f2cf842d47 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-92
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-76 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-3955 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-38 |
| filingDate |
2018-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_645e6a2b07f2416cd2ee6575652eff51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11e4823a5ad1c0349c2b978f8449206e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_74b47aaf7a45e34ab68a21392eff6bb7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b516241ef41c9065dca063c037b40f7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c64924ec62c7af23a6f729a0cc80fc97 |
| publicationDate |
2019-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2019030706-A1 |
| titleOfInvention |
ANTI-THROMBIN ANTIBODY MOLECULES AND METHODS OF USE IN ORTHOPEDIC SURGERY |
| abstract |
The present invention provides isolated anti-thrombin antibodies that recognize the thrombin exosite-1 epitope and selectively inhibit thrombin without causing bleeding. These antibody molecules can be used in the treatment and prevention of thrombosis, embolism and other thrombin-mediated disease states. In particular, the present invention relates to the clinically safe and effective proven use of anti-thrombin antibody molecules in patients undergoing orthopedic surgery, including total knee replacement surgery (TKP) and Total hip replacement surgery (THA). |
| priorityDate |
2017-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |