| abstract |
The following polypeptide or salt thereof having strong cytoprotective activity and sufficiently reduced blood anticoagulant activity: X1 CPEGYILDDGX2ICTDIDE (second and 14th N-terminal cysteine residues (C) form an S-S bond And the S—S bond is a group represented by CHR 1 —CHR 2 (R 1 and R 2 each represents a hydrogen atom, an alkyl group having 1 to 4 carbon atoms, a halogen atom, a hydroxyl group, or an amino group) X1 is absent or represents a glutamic acid residue (E) or an aspartic acid residue (D); X2 represents a phenylalanine residue, an alanine residue or a tyrosine residue) |