| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_82bedf03ef5cd9f5cca99088b48411e3 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-20 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y207-1101
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1137 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate |
2018-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38c7a71bb2570750b7577fef59668038
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2621d1dfb740724de1a63dde688b8c29
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_412fe426911d28a14deb8717aa7f9367
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8bd81a97a62a7d3afe04b37a09a1bc96
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9b911efacfc946d8763f3630ca7f9c5 |
| publicationDate |
2019-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2019025565-A1 |
| titleOfInvention |
DOUBLE INHIBITION OF IKK1 AND IKK2 FOR THE TREATMENT OF PROLIFERATIVE DISEASES |
| abstract |
The present invention relates to the dual inhibition of kB (IKK) 1 and IKK2 Kinase Inhibitor in a biological cell for the treatment of tumors. The invention provides compositions comprising IKK1 and IKK2 antagonists for use in the medical treatment of proliferative disorders, particularly for the treatment of cancer. Most recommended in the context of the invention is a gene editing approach for targeted simultaneous knockout of IKK1 and IKK2 genes in a cell associated with the proliferative disorder. |
| priorityDate |
2017-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |