Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_41dc944eb862e236c0aad17f9f1df8cf http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_faafbacd692f8f584c47fcca402df63a |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-317 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-351 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-115 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7088 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-115 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088 |
filingDate |
2018-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e851126c7e2a68168fcfb5733bb5d642 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8dfdadda8f60b77832da5b5dcf3157c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b53ee16f7d295d0e414696487b6d0d0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ae144d948a424590689fe3a73c561ed http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56f6f60d669f315e343f440616b098b3 |
publicationDate |
2019-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2019022986-A1 |
titleOfInvention |
NUCLEIC ACID COMPOSITIONS AND METHODS OF INHIBITING D-FACTOR |
abstract |
The present invention provides methods and compositions for inhibiting the alternative complement pathway. The methods and compositions generally involve the use of aptamers to inhibit complement factor D. The invention further relates to anti-factor D aptamers for the treatment of age-related dry macular degeneration, atrophy. geographic, age-related wet macular degeneration, Stargardt's disease and other eye disorders or diseases. In some cases, anti-fD aptamer consensus sequences are described. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10428330-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11274307-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11466276-B2 |
priorityDate |
2017-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |