http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019017691-A3

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filingDate 2018-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c554d6207e4ff85bb2ad993ebb8900c
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publicationDate 2019-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2019017691-A3
titleOfInvention METHOD OF DIFFERENTIATING HUMAN INDUCED PLURIPOTENT STRAIN CELL IN DERMAL PAPER PRECURSOR CELL AND USE THEREOF
abstract The present invention relates to a medium-type composition for the differentiation of a human-induced pluripotent stem cell into a dermal papilla precursor cell, a differentiation method and a use for inducing the neogenesis of hair follicles using said precursor cell. differentiated dermal papillae. The present inventors have developed a method of differentiating a human-induced pluripotent stem cell into a dermal papilla precursor cell having hair follicle forming capacity and a dermal papilla precursor cell specific differentiation medium composition. the above differentiation, and have effectively induced the neogenesis of hair follicles consisting solely of human cells, without conventional murine-human hybrid hair follicles, using said human induced dermal papilla precursor cell and a precursor cell. human induced epidermis obtained via said differentiation method. The human hair follicle tissue obtained by applying the dermal papillary precursor cell differentiation technique of the present invention should be useful as a therapeutic method for patients suffering from hair loss by overcoming the limitations of the treatments against the loss of hair. hair.
priorityDate 2017-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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