http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019014432-A1

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publicationDate 2019-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2019014432-A1
titleOfInvention CENTRAL BLOOD PRESSURE MONITORING THROUGH A STANDARD AUTOMATIC CUFF
abstract Current oscillometric devices to monitor central blood pressure (PS) maintain cuff pressure at a constant level to acquire a pulse volume plethysmography waveform (PVP) and calibrate to estimated brachial PS levels with population average methods. A physiological process has been developed to further advance central PS measurement. A patient specific method was applied to estimate brachial PS levels from a cuff pressure waveform obtained during conventional deflation through a nonlinear arterial compliance model. A physiology-inspired method was then used to extract the PVP waveform from the same waveform through an ensemble average and calibrate it to the brachial PS levels. A method based on a wave reflection model was then used to define a variable transfer function, which was applied to the calibrated waveform to derive the central PS.
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