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filingDate 2018-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a42183dcf4007727e5c4c0896baee6bc
publicationDate 2019-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2019014375-A1
titleOfInvention SMALL RNA PREDICTORS FOR HUNTINGTON'S DISEASE
abstract The present invention provides methods and kits for assessing Huntington's disease (HD) activity, including patients receiving HD treatment or HD candidate therapy, as well as animal and cellular models. . More particularly, the present invention relates to biomarkers (RNA predictors) that are binary predictors of disease activity, and are useful for detecting and / or assessing disease stage, grade, progression, and prognosis. HD and a response to a therapy or a candidate therapy. Biomarkers are also useful in the context of drug discovery and clinical trials to identify candidate drug interventions (or other therapies) that are useful for the treatment of the disease.
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