abstract |
The invention relates to oxadiazole linkers and their use, more particularly the invention relates to compounds represented by Formulas I, II and III, and their use in the preparation of antibody-drug conjugates (ADC). The ADCs obtained from said oxadiazole linkers exhibit high homogeneity and stability, and could be used effectively for the treatment of various diseases including tumors. The definition of groups in formulas I, II and III is identical to that given in the description. |