| abstract |
There is provided a medical compound comprising a synthetic flavone derivative, according to the formula (I) with allotment in position C-3 of a group as shown below: Formula (I) wherein at least two of R2-R6 a re H, and the remaining are independently selected from: H, OH, R1, OR1, NO2, NH2, NHR1, F, CI, Br, I, where R1 is a radical. Also provided are dimeric, trimeric and tetrameric compounds, where two or more quercetin units are linked through position 3 and a spacer to a central linker (scaffold). The medical compounds may be used for the treatment of malignant tumours, in particular malignant epithelial tumours, such as colon carcinoma, melanoma and/or skin squamous carcinoma, lung carcinoma, mammary carcinoma, basal cell carcinoma (basalioma). |