| abstract |
The present invention relates to a method of purifying a sample containing nucleic acids to obtain isolated nucleic acids of a desired size range, either above a cut size, below a cut, or within a defined band of sizes, comprising: a) combining a sample containing a nucleic acid with a binding buffer to provide a binding mixture; b) contacting the bonding mixture with a nanomembrane of silica, the nanomembrane of silica adsorbs the nucleic acids of the binding mixture in a desired size range; and c) separating the bound nucleic acid from the remaining sample. The invention also relates to kits comprising a silica nanomembrane, a binding buffer and one or more wash buffers. |