http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019005806-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_186da66fa2f732fc0d7a2297e5fc1a41 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2537-159 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2563-143 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2563-149 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6816 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6806 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-34 |
| filingDate | 2018-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38aed115d75a226910e0ee7e2248e4b3 |
| publicationDate | 2019-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2019005806-A1 |
| titleOfInvention | BODY FLUID TARGET ENRICHMENT |
| abstract | The present invention relates to methods for capturing target nucleic acid directly from body fluid samples, without the need for certain complex sample preparation steps, using Cas endonuclease to bind to the sequences of the sample. target nucleic acids. The Cas proteins, together with their sequence-specific guide RNAs, can be introduced directly into the sample, with the Cas binding proteins at the ends of a target nucleic acid. The target nucleic acid is thus isolated or enriched in a sequence-specific manner. The target nucleic acid can then be subjected to any appropriate assay for detection or analysis, such as amplification or sequencing. The target nucleic acid can be enriched by digestion of other unbound nucleic acids present in the sample with an exonuclease. The bound Cas proteins prevent the exonuclease from digesting the target nucleic acid, leaving only the target nucleic acid substantially present in the sample. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11384383-B2 |
| priorityDate | 2017-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 60.