| abstract |
Provided is an anti-GITR antibody, an antigen-binding fragment thereof, and a medical use thereof, further comprising a chimeric antibody, a humanized antibody comprising the anti-GITR antibody CDR region, and an anti-GITR antibody and an antigen-binding fragment thereof. Pharmaceutical compositions, and their use in the preparation of anticancer drugs. In particular, there is provided the use of a humanized anti-GITR antibody for the manufacture of a medicament for the treatment of a GITR mediated disease or condition. |