| abstract |
Provided is a G crystal form of an imidazoisoindole derivative free base having a chemical structure as shown in formula (I) and a chemical name of (S)-2-(4-(4) -(4-(6-Fluoro-5H-imidazo[5,1-a]isoindol-5-yl)piperidin-1-yl)phenyl)-1H-pyrazol-1-yl)ethanol. Providing the use of the G crystalline form of the compound in a pharmaceutical composition and the G crystalline form and composition having IDO (melamine-pyrrole-2,3-dioxygenase) mediated color ammonia in the preparation of the treatment Acid metabolism pathway pathological characteristics of drug use in diseases. The G crystal form of the compound has good stability, and the crystallization solvent used has low toxicity and low residue, and can be better used for clinical treatment. |