| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_321b10c632ca3a14bdb685ff273c4f4c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c9faf891bdd318970bba39c126b05599 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-734
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-92
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-73
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-732
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-71
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-72
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-622
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-524
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-526 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2809 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 |
| filingDate |
2018-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8739e1aa7faaea2be3cd9100dde79c5e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa6be777d09c9996307b0cee71827fb3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f215c0d67d58253ce0d669cdc3178840
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e3ffec6da73604d5f4273a615a32d62 |
| publicationDate |
2018-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2018237364-A1 |
| titleOfInvention |
BISPECIFIC ANTI-GLOBO H ANTIBODY AND ANTI-CD3 FUSION FC-SCFV ASYMMETRIC HETERODIMER AND ASSOCIATED USES IN ANTICANCER THERAPY |
| abstract |
The present invention relates to a bispecific anti-Globo H antibody which comprises an anti-Globo H antibody that specifically binds to Globo H; and a T cell targeting domain fused to a CH3 domain of an anti-Globo H antibody heavy chain, the T cell targeting domain specifically binding to an antigen on T cells; and the anti-Globo H antibody comprising mutations at an effector binding site such that the bispecific anti-Globo H antibody has decreased effector function. The T cell targeting domain is ScFv or Fab from an anti-CD3 antibody. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021162098-A1 |
| priorityDate |
2017-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |