| abstract |
The present invention relates to broad spectrum HIV neutralizing antibodies, compositions comprising them and methods of use thereof. More specifically, the invention provides isolated anti-HIV antibodies that can neutralize at least 95% of the HIV pseudorabies listed in Table 1 and neutralize 100% of the clades B, G and D HIV viruses listed in the table. 1 with an IC50 value less than 50 μg / mL. The invention further relates to the sequences, particularly the complementarity-determining region (CDR) sequences of antibodies described. |