Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf2c54d5a3e3f639740ecbfbb72fd4b4 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-7007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2013 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2054 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0056 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4045 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-38 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4045 |
filingDate |
2018-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_095e7ddc3eb60a59e8f946eac5339369 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de16d0683c8606fcacc90bab5a7c57ae http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53c8e91edfaa7edcccdd4711364cc85b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_05414423c108aa9c066b2422c8abbca0 |
publicationDate |
2018-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2018236678-A1 |
titleOfInvention |
ORAL DISSOLUTION MELATONIN FORMULATION WITH ACIDIFYING AGENT THAT MAKES MELATONIN SOLUBLE IN SALIVA |
abstract |
A composition comprises a pharmaceutical dosage form configured to integrate into saliva and maintain a pH of 4 or less within the saliva during the time when the dosage form is dissolved therein. The dosage form comprises a therapeutically effective amount of melatonin in a carrier matrix, a disintegrating agent, and a sufficient amount of acid to impart pH to the saliva. The amount of the disintegrating agent is sufficient to cause complete disintegration of the dosage form in saliva within ten minutes of contact with saliva. |
priorityDate |
2017-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |