Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f97f0fa258a008bf056ad04b7f380dda |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-8831 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2560-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-976 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-8818 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6857 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-7233 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6848 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6854 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-62 |
filingDate |
2017-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d0d3e565f3c6eaf94f672fef83c25ba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_21b30d1cd9bff9f121abd11191304483 |
publicationDate |
2018-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2018235228-A1 |
titleOfInvention |
Method for quantifying monoclonal antibody bound to antigen or anti-antibody |
abstract |
The present invention relates to a method in which a porous body in the pores of which a monoclonal antibody of interest is immobilized is contacted with nanoparticles on which a protease is immobilized in a liquid to effect selective digestion of the monoclonal antibody with the protease, then a peptide fragment produced by the digestion is detected by coupling liquid chromatography-mass spectrometry (LC-MS), the monoclonal antibody being digested with the protease in the presence of an antibody capable of binding to the antibody monoclonal specifically or to a target molecule for the monoclonal antibody. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11708572-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10704021-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11377651-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10975368-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10785574-B2 |
priorityDate |
2017-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |