| abstract |
The invention relates to a dual drug-like HMG-CoA reductase inhibitor, which is a combination drug formed by the chain linkage of a fibrate compound selected from any of gemfibrosil, clofibric acid, fenofibrate acid, bezafibrate or ciprofibrate, or nicotinic acid or acipimox and a statin, by a linker Br- (CH2) n-Br, Br- (CH2) n-OH or Br- (CH2) n- NH2, n being an integer from 1 to 30, and the statin being mevastatin, lovastatin, simvastatin, pravastatin, fluvastatin, cerivastatin, atorvastatin, rosuvastatin or pitavastatin. |