| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fab5a78161702097f97524ce6e5cdcd7 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6869
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1241
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1058
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-902
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-907 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 |
| filingDate |
2018-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_93ed351187ebc3be90b742b9f00de7d3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bedae2a5b62ead3d0c8f7fea510ab2f5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_333938476e970e80ac01d6e48c89a417 |
| publicationDate |
2018-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2018229226-A1 |
| titleOfInvention |
Methods and means for genetic alteration of genomes utilizing designer dna recombining enzymes |
| abstract |
The invention provides methods and means for specifically altering the DNA sequence in a genome, in particular for genome editing by deleting or replacing a sequence of interest. Advantageously, the invention uses two non-identical sequences naturally occurring in a genome as target sites two which DNA-recombining enzymes are generated. The invention is in particular useful for medicine, in particular to repair a mutation in a genome or to delete predefined genetic material from cells or tissue and to cure diseases. An advantage of the invention is that it allows precise site directed altering of DNA without engaging host DNA repair pathways and thereby works without inducing random insertions and deletions (indels). |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11324839-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11766490-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11684680-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023084099-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021110846-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2606844-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3831939-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11602569-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021055760-A1 |
| priorityDate |
2017-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |