| abstract |
A gastric tract acid (GTA) compound having the structure of formula I, as well as salts, esters, prodrugs, or labelled derivatives thereof, are provided. Such GTA compounds may be used for determining GTA levels of a sample, for diagnosing a subject as having or being at risk of developing colorectal cancer, or for raising antibodies. Antibodies, or fragments thereof, which specifically bind to the GTA of formula I are described, as well as uses of such antibodies or fragments for determining GTA levels in a sample, or for diagnosing a subject as having or being at risk of developing colorectal cancer. Kits comprising such GTA compounds and/or antibodies are also provided. |