| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c69def3bf2d75c80ac422fcf66bf0e48 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-42 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6848
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6803
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5308 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
| filingDate |
2018-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_774970f30209945dff9216225bbf7fe9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f31f27d4378f0a469d5ffe80fa0036c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4589992d731f8282b1b3512f735d5081
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c4e3746111c6b72a73d1a3409d79f54 |
| publicationDate |
2018-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2018227253-A1 |
| titleOfInvention |
Method for determining the amount of cytidine analogues |
| abstract |
The present application describes a method for determining the amount of a cytidine analogue in a mixture, the cytidine analogue having an optionally substituted unsaturated 6-membered heterocyclyl ring comprising 3 ring carbon atoms and 3 ring nitrogen atoms, the method comprising treating the mixture to reduce the 6-membered heterocyclyl ring of the cytidine analogue and then determining the amount of the reduced cytidine analogue. In particular, the method is useful for determining the amount of 5- azacitidine (AZA) incorporated into the RNA and/or 5-aza-2'-deoxycytidine (DAC) incorporated into the DNA. The mixture is taken from a cellular extract, cytoplasmic extract and/or a nucleic acid extract. |
| priorityDate |
2017-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |