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publicationDate 2018-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2018223003-A1
titleOfInvention Detection of par in the csf of patients with parkinson's disease
abstract Poly(ADP-ribose) (PAR) is a protein implicated in numerous neurodegenerative disease states including Parkinson's disease (PD). To date, no routine laboratory test has been developed to diagnosis, assess or monitor patients suffering from PD. Disclosed herein a novel method to assess the PAR concentration in the cerebral spinal fluid (CSF) of a patient and correlate that concentration to the medical condition of a patient with PD. Also disclosed is the use of PAR as a biomarker for PD.
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