http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018222345-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d6baba7c6ceb747e544d919b5a53098e |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01J49-0031 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01J49-0045 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01J49-005 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/H01J49-00 |
filingDate | 2018-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4179011a57433eb1d56a82fbd96396e9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_516ec37b2e210d738260c5e3fb941274 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cbdcdd9543d615d751c30b2fb24fc8a5 |
publicationDate | 2018-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2018222345-A1 |
titleOfInvention | Automated determination of mass spectrometer collision energy |
abstract | The present disclosure establishes new dissociation parameters that may be used to determine the collision energy (CE) needed to achieve a desired extent of dissociation for a given analyte precursor ion using collision cell type collision-induced dissociation. This selection is based solely on the analyte precursor ion's molecular weight, MW, and charge state, z. Metrics are proposed that may be used as a parameter for the "extent of dissociation", and then predictive models are developed of the CEs required to achieve a range of values for each metric. Each model is a simple smooth function of only MW and z of the precursor ion. Coupled with a real-time spectral deconvolution (m/z to mass) algorithm, methods in accordance with the invention enable control over the extent of dissociation through automated, real-time selection of collision energy in a precursor- dependent manner. |
priorityDate | 2017-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1261.