| abstract |
Disclosed is a composition comprising transdifferentiated human insulin producing cells (IPCs), human endothelial colony forming cells (ECFCs), and human mesenchymal stem cells (MSCs), wherein said ECFCs and MSCs enhance IPCs transdifferentiation, and also promote de novo blood vessel formation when implanted in an organism. Also disclosed here is ECFCs and MSCs conditioned media, and methods of enhancing cell maturation by using said conditioned media. |