| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dc18752b143a0edc509fc16ba761a2af |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6421
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-399 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-552
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-3577
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-523 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-552
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-3577
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-52 |
| filingDate |
2018-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_486fa01568c1f2d3457fe8d52aa6bb1b |
| publicationDate |
2018-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2018219969-A1 |
| titleOfInvention |
Biosensor for conformation and secondary structure analysis |
| abstract |
The invention provides an infrared detection system for conformation and secondary structure analysis, notably for the direct non-invasive qualitative secondary structure analysis of a single selected protein within a complex mixture, as e.g. a body fluid, by vibrational spectroscopic methods utilizing a quantum- cascade laser. For the analysis it is not required that the selected substance be isolated, concentrated, or pretreated by a special preparative procedure. A difference-spectrum between the unbound and antibody-bound protein of interest is performed by which the much larger background absorbance is cancelled. The presented quantum- cascade laser set-up provides sufficient S/N and stability to subtract the several orders of magnitude larger background absorbance. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11592451-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112185470-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112185470-B |
| priorityDate |
2017-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |