Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_09fc02a407043ca0a10e2dbe5fcb6159 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cc64a0225ee1b588c1d7af77250eee01 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-00 |
filingDate |
2018-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c208c83514b1e4c315b529d2ac901f17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe3d4b7c8b2e7f763f07407c464dce9d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a5edf02590980977de031f5127f5bd1 |
publicationDate |
2018-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2018213219-A1 |
titleOfInvention |
Pyrido[2,3-d]pyrimidin-7ones and related compounds as inhibitors of protein kinases |
abstract |
Identified compounds demonstrate protein kinase inhibitory activity. More specifically, the compounds having the structures below (I) are demonstrated to inhibit receptor interacting kinase 2 (RIPK2) and/or Activin-like kinase 2 (ALK2). Compounds that are either dual RIPK2/ ALK2 inhibitors or that preferentially inhibit RIPK2 or ALK2 could provide therapeutic benefit. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020132384-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11168093-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020232190-A1 |
priorityDate |
2017-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |