Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8fb9f44db08d1c42a53f3d28eaae416f |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-216 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-216 |
filingDate |
2018-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b24759d20a9ba90d42082511039f546 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_422e5945948ddac5177843957eaef205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ebf8014c9c0e56797c741f9ce9d5650d |
publicationDate |
2018-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2018207792-A1 |
titleOfInvention |
Blood-brain barrier protecting agent |
abstract |
Provided is a substance that suppresses a breakage of the blood-brain barrier. A Claudin-5 expression promoter that comprises chlorogenic acid or a salt thereof as an active ingredient. A brain HMGB1 expression inhibitor that comprises chlorogenic acid or a salt thereof as an active ingredient. A blood-brain barrier protecting agent that comprises chlorogenic acid or a salt thereof as an active ingredient. An agent for preventing or ameliorating dysfunction of the blood-brain barrier, said agent comprising chlorogenic acid or a salt thereof as an active ingredient. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020239356-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-3096579-A1 |
priorityDate |
2017-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |